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GalaFLEX™ Scaffold is an open pore monofilament scaffold composed of poly-4-hydroxybutyrate (P4HB), a fully-absorbable, biologically-derived polymer produced from the monomer form 4HB—a naturally occurring human metabolite found in the brain, heart, liver, kidney and muscle.
GalaFLEX™ Scaffold degrades gradually and predictably within 18 to 24 months, and is eliminated from the body as water and carbon dioxide through natural physiologic pathways.
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2,3,4
A fully-absorbable, biologically-derived polymer
What is P4HB?
Hint: It’s not animal, cadaver or even synthetic

A fully-absorbable, biologically-derived polymer
GalaFLEX™ Scaffold is an open pore monofilament scaffold composed of poly-4-hydroxybutyrate (P4HB), a fully-absorbable, biologically-derived polymer produced from the monomer form 4HB—a naturally occurring human metabolite found in the brain, heart, liver, kidney and muscle.
GalaFLEX™ Scaffold degrades gradually and predictably within 18 to 24 months, and is eliminated from the body as water and carbon dioxide through natural physiologic pathways.
1
2,3,4


BIOLOGICALLY-DERIVED
BIOABSORBABLE
A fully-absorbable, biologically-derived polymer
GalaFLEX™ Scaffold is an open pore monofilament scaffold composed of poly-4-hydroxybutyrate (P4HB), a fully-absorbable, biologically-derived polymer produced from the monomer form 4HB—a naturally occurring human metabolite found in the brain, heart, liver, kidney and muscle.¹
GalaFLEX™ Scaffold degrades gradually and predictably within 18 to 24 months, and is eliminated from the body as water and carbon dioxide through natural physiologic pathways.²'³'⁴


BIOLOGICALLY-DERIVED
BIOABSORBABLE
Absorption of P4HB naturally initiates an early shift of macrophages from a pro-inflammatory phenotype to a pro-remodeling phenotype. Also known as "repair" macrophages, these pro-remodeling macrophages help to regenerate native tissue.⁴'⁵'⁶
How P4HB works
Early repair response


Long-term support ²'⁴'⁷
After GalaFLEX™ Scaffold is implanted, there is a gradual transfer of the load from the scaffold to the ingrown tissue.²'⁴
Absorption of P4HB naturally initiates an early shift of macrophages from a pro-inflammatory phenotype to a pro-remodeling phenotype. Also known as "repair" macrophages, these pro-remodeling macrophages help to regenerate native tissue.
How P4HB works
Early repair response
4,5,6
After GalaFLEX™ Scaffold is implanted, there is a gradual transfer of the load from the scaffold to the ingrown tissue.
2,4
Long-term support
2,4,7
Designed to minimize risk of infection and encourage natural healing response.
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Monofilament design







GalaFLEX™ Scaffold maintains greater than 70% of its strength at 12 weeks in vivo.⁴
Tissue repaired with P4HB has been shown to be 3-4x stronger than native tissue.²'⁴'⁷
GalaFLEX™ Scaffold maintains greater than 70% of its strength at 12 weeks in vivo.